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Publications

Underline indicates trainee with significant mentoring.

[Abstract] Circulating tumor DNA (ctDNA), dormant disseminated tumor cells (DTCs) and recurrence outcomes in breast cancer survivors on the SURMOUNT Study

Clinical Cancer Research, 2025.

Eleanor Taranto, Nicholas J. Seewald, Lauren J. Bayne, Emma Walinsky, Shannon Deluca, Natalie NC. Shih, Pauleen Sanchez, Isoris Nivar, Bana Ambasager, Clodagh Murray, Amber Chevalier, Christopher G. Smith, Igor Makhlin, Killian Rohn, Brooke L. Goodspeed, Jessica Savage, Paul Wileyto, Jianping Wang, George Belka, Elizabeth Chislock, Lindsay R Berry, Don Berry, Anupma Nayak, Michael Feldman, Amy S. Clark, Lewis A. Chodosh, Angela DeMichele

Use of Life Support and Outcomes Among Patients Admitted to Intensive Care Units

JAMA, 2025.

Emily E. Moin, Nicholas J. Seewald, Scott D. Halpern

Corticosteroid-dependent association between prognostic peripheral blood cell-free DNA levels and neutrophil-mediated NETosis in patients with glioblastoma

Clinical Cancer Research, 2025.

Jacob E. Till, Nicholas J. Seewald, Zachariya Yazdani, Zhuoyang Wang, Dominique Ballinger, Heather Samberg, Siri Dandu, Camilla Macia, Melinda Yin, Aseel Abdalla, Timothy Prior, Shivani Shah, Thara Patel, Emily McCoy, Maikel Monsour, Carson A. Wills, Veronica Bochenek, Jonathan Serrano, Matija Snuderl, Richard E. Phillips, Donald M. O’Rourke, Nduka M. Amankulor, Ali Nabavizadeh, Arati S. Desai, Kandace Gollomp, Zev A. Binder, Wanding Zhou, Stephen J. Bagley, Erica L. Carpenter

Development and Validation of a Simple Model to Predict Patient Height

medrXiv, 2025.

Emily E. Moin, Nicholas J. Seewald, Scott D. Halpern

[Abstract] Real-world time on treatment (rwTOT) with first-line (1L) enfortumab vedotin and pembrolizumab (EV+P) after U.S. Food and Drug Administration approval for advanced urothelial cancer (aUC)

Journal of Clinical Oncology, 2025.

Melanie Mayer, Nicholas J. Seewald, Ernesto Ulloa Perez, Blanca Homet Moreno, Chethan Ramamurthy, Aram Babcock, Haojie Li, Ronac Mamtani

[Abstract] Does liver tumor morphology predict outcomes after LDT, PRRT or captem?

Endocrine Abstracts, 2024.

Cathal O'Leary, David Tischfield, Rony Avritscher, Ghassan El-Haddad, Nicholas Fidelman, Ricardo Garcia-Monaco, Nimrata Vijayvergia, Pamela Kunz, Nicholas J. Seewald, Michael C. Soulen

Target Trial Emulation for Evaluating Health Policy

Annals of Internal Medicine, 2024.

Nicholas J. Seewald, Emma E. McGinty, Elizabeth A. Stuart

[Abstract] LODESTAR: A Single Arm Phase II Study of Rucaparib in Solid Tumors with Pathogenic Germline or Somatic Variants in Homologous Recombination Repair (HRR) Genes

Cancer Research, 2024.

Sriram Anbil, Nicholas J. Seewald, Kevin Lin, Marcia Craib, Christy Connor, Heidi Giordano, Karen McLachlan, Tanya Kwan, Lara Maloney, Hanna Tukachinsky, Alexa Schrock, Shuoguo Wang, Ethan Sokol, Brennan Decker, Katherine Nathanson, Susan Domchek, Kim Reiss

Effects of Texas State Agency Integration on Mental Health Service Use Among Individuals with Co-occurring Cognitive Disabilities and Mental Health Conditions

Community Mental Health Journal, 2024.

Elizabeth M. Stone, Andrew D. Jopson, Nicholas J. Seewald, Elizabeth A. Stuart, Elizabeth Wise, Alexander D. McCourt, Danielle German, Emma E. McGinty

[Abstract] Association of BRCA1/2 pathogenic variants with primary tumor location and metastatic organotropism in pancreatic adenocarcinoma

Journal of Clinical Oncology, 2024.

Ryan Hood, Srishti Rathore, Nicholas J. Seewald, Kim Anna Reiss

[Abstract] Interaction of BRCA1 vs BRCA2 pathogenic variants with primary tumor location in pancreatic cancer

Journal of Clinical Oncology, 2024.

Ryan Hood, Nicholas J. Seewald, Srishti Rathore, Kim Anna Reiss

Shared Control Individuals in Health Policy Evaluations with Application to Medical Cannabis Laws

arXiv, 2023.

Nicholas J. Seewald, Emma E. McGinty, Kayla Tormohlen, Ian Schmid, Elizabeth A. Stuart

Effects of U.S. State Medical Cannabis Laws on Treatment of Chronic Noncancer Pain

Annals of Internal Medicine, 2023.

Emma E. McGinty, Kayla N. Tormohlen, Nicholas J. Seewald, Mark C. Bicket, Alexander D. McCourt, Lainie Rutkow, Sarah A. White, Elizabeth A. Stuart

Adaptive Interventions for a Dynamic and Responsive Public Health Approach

American Journal of Public Health, 2023.

Nicholas J. Seewald

Design considerations for preparation, optimization, and evaluation of digital therapeutics

Digital Therapeutics for Mental Health and Addiction, 2022.

Shawna N. Smith, Nicholas J. Seewald, Predrag Klasnja

Scaling Interventions to Manage Chronic Disease: Innovative Methods at the Intersection of Health Policy Research and Implementation Science

Prevention Science, 2022.

Emma E. McGinty, Nicholas J. Seewald, Sachini Bandara, Magdalena Cerdá, Gail L. Daumit, Matthew D. Eisenberg, Beth Ann Griffin, Tak Igusa, John W. Jackson, Alene Kennedy‑Hendricks, Jill Marsteller, Edward J. Miech, Jonathan Purtle, Ian Schmid, Megan S. Schuler, Christina T. Yuan, Elizabeth A. Stuart

Effects of State Opioid Prescribing Laws on Use of Opioid and Other Pain Treatments Among Commercially Insured U.S. Adults

Annals of Internal Medicine, 2022.

Emma E. McGinty, Mark C. Bicket, Nicholas J. Seewald, Elizabeth A. Stuart, G. Caleb Alexander, Colleen L. Barry, Alexander D. McCourt

Sequential, Multiple Assignment, Randomized Trials (SMART)

Principles and Practice of Clinical Trials, 2021.

Nicholas J. Seewald, Olivia Hackworth, Daniel Almirall

Design and Analytic Considerations for Sequential, Multiple-Assignment Randomized Trials with Longitudinal Outcomes

University of Michigan, 2021.

Nicholas J. Seewald

Sample Size Considerations for Comparing Dynamic Treatment Regimens in a Sequential Multiple-Assignment Randomized Trial with a Continuous Longitudinal Outcome

Statistical Methods in Medical Research, 2020.

Nicholas J. Seewald, Kelley M. Kidwell, Inbal Nahum-Shani, Tianshuang Wu, James R. McKay, Daniel Almirall

Practical Considerations for Data Collection and Management in Mobile Health Micro-Randomized Trials

Statistics in Biosciences, 2019.

Nicholas J. Seewald, Shawna N. Smith, Andy Jinseok Lee, Predrag Klasnja, Susan A. Murphy

Design and Analysis Considerations for Comparing Dynamic Treatment Regimens with Binary Outcomes from Sequential Multiple Assignment Randomized Trials

Journal of Applied Statistics, 2018.

Kelley M. Kidwell, Nicholas J. Seewald, Qui Tran, Connie Kasari, Daniel Almirall

Efficacy of Contextually Tailored Suggestions for Physical Activity: A Micro-Randomized Optimization Trial of HeartSteps

Annals of Behavioral Medicine, 2018.

Predrag Klasnja, Shawna Smith, Nicholas J. Seewald, Andy Lee, Kelly Hall, Brook Luers, Eric B. Hekler, Susan A. Murphy

Prospective Assessment of Patient-Reported Outcomes and Estradiol and Drug Concentrations in Patients Experiencing Toxicity from Adjuvant Aromatase Inhibitors

Breast Cancer Research and Treatment, 2017.

Kunal C. Kadakia, Kelley M. Kidwell, Nicholas J. Seewald, Claire F. Snyder, Anna Maria Storniolo, Julie L. Otte, David A. Flockhart, Daniel F. Hayes, Vered Stearns, N. Lynn Henry

Sequential Multiple Assignment Randomized Trials: An Opportunity for Improved Design of Stroke Reperfusion Trials

Journal of Stroke and Cerebrovascular Diseases, 2017.

William J. Meurer, Nicholas J. Seewald, Kelley Kidwell

Design Lessons from a Micro-Randomized Pilot Study in Mobile Health

Mobile Health, 2017.

Shawna N. Smith, Andy Jinseok Lee, Kelly Hall, Nicholas J. Seewald, Audrey Boruvka, Susan A. Murphy, Predrag Klasnja

MRT-SS Calculator: An R Shiny Application for Sample Size Calculation in Micro-Randomized Trials

arXiv [stat.ME], 2016.

Nicholas J. Seewald, Ji Sun, Peng Liao

Patient-Reported Outcomes and Early Discontinuation in Aromatase Inhibitor-Treated Postmenopausal Women with Early Stage Breast Cancer

The Oncologist, 2016.

Kunal C. Kadakia, Claire F. Snyder, Kelley M. Kidwell, Nicholas J. Seewald, David A. Flockhart, Todd C. Skaar, Zereunesay Desta, James M. Rae, Julie L. Otte, Janet S. Carpenter, Anna M. Storniolo, Daniel F. Hayes, Vered Stearns, N. Lynn Henry

[Abstract] CYP3A4*22 polymorphism is associated with increased exemestane concentrations in postmenopausal breast cancer patients

Cancer Research, 2016.

Daniel L. Hertz, Kelley M. Kidwell, Nicholas J. Seewald, Christina L. Gersch, Zeruesenay Desta, David A. Flockhart, Ana-Maria Storniolo, Vered Stearns, Todd C. Skaar, Daniel F. Hayes, N. Lynn Henry, James M. Rae"

[Abstract] Crossover from One Aromatase Inhibitor (AI) to Another in the Exemestane and Letrozole Pharmacogenetics (ELPh) Trial

Journal of Clinical Oncology, 2016.

Kunal C. Kadakia, Kelley M. Kidwell, Nicholas J. Seewald, Claire Frances Snyder, David A. Flockhart, Janet S. Carpenter, Julie L. Otte, Daniel F. Hayes, Anna Maria Storniolo, Vered Sterns, Norah Lynn Henry

Polymorphisms in Drug-Metabolizing Enzymes and Steady-State Exemestane Concentration in Postmenopausal Patients with Breast Cancer

The Pharmacogenomics Journal, 2016.

Evidence for Association of SNPs in ABCB1 and CBR3, but Not RAC2, NCF4, SLC28A3 or TOP2B, with Chronic Cardiotoxicity in a Cohort of Breast Cancer Patients Treated with Anthracyclines

Pharmacogenomics, 2016.

Daniel L. Hertz, Megan v. Caram, Kelley M. Kidwell, Jacklyn N. Thibert, Christina Gersch, Nicholas J. Seewald, Jeffrey Smerage, Melvyn Rubenfire, N. Lynn Henry, Kathleen A. Cooney, Monika Leja, Jennifer J. Griggs, James M. Rae

[Abstract] Associations between treatment-emergent symptoms and early discontinuation of aromatase inhibitor (AI) therapy

Journal of Clinical Oncology, 2015.

Kunal C. Kadakia, Claire Frances Snyder, Kelley M Kidwell, Nicholas J. Seewald, Anna Maria Storniolo, David A. Flockhart, Janet S. Carpenter, Daniel F. Hayes, Vered Stearns, Norah Lynn Henry

[Abstract] Primary CNS Lymphoma; A Review of the University of Michigan Experience 2004-2013

Journal of Clinical Oncology, 2015.

Aaron G. Mammoser, Shaio-Pei S. Weathers, Nicholas J. Seewald, Jeremy M. G. Taylor, Larry Junck

Tris(3,5-Di-Tert-Butylcatecholato)Molybdenum(VI): Lewis Acidity and Nonclassical Oxygen Atom Transfer Reactions

Inorganic Chemistry, 2013.

Amanda H Randolph, Nicholas J. Seewald, Karl Rickert, Seth N Brown

Nonclassical Oxygen Atom Transfer Reactions of Oxomolybdenum(VI) Bis(Catecholate)

Chemical Communications, 2012.

Travis Marshall-Roth, Sean C Liebscher, Karl Rickert, Nicholas J. Seewald, Allen G Oliver, Seth N Brown