DTRs

Adaptive Interventions for a Dynamic and Responsive Public Health Approach
A comment on Wang and Chakraborty (2023) in which I argue that adaptive interventions have the potential to lead us towards a vision of …
Nicholas J. Seewald
Cite DOI PubMed
Adaptive Interventions for a Dynamic and Responsive Public Health Approach
A brief introduction to multi-stage trials for developing dynamic treatment regimens
A 45-minute seminar on dynamic treatment regimens (DTRs) and sequential multiple-assignment randomized trials geared towards a clinical audience.
Mar 11, 2022 9:00 AM — 10:00 AM Virtual
Nicholas J. Seewald
Slides
A brief introduction to multi-stage trials for developing dynamic treatment regimens
Building effective adaptive interventions in mental health services research
The Johns Hopkins ALACRITY Center for Health and Longevity in Mental Illness hosts trainings for researchers interested in methods used in health services research. This series of videos provides an introduction to the use of SMARTs to build high-quality adaptive interventions for health services.
Feb 11, 2022
Nicholas J. Seewald
Video Slides
Building effective adaptive interventions in mental health services research
A brief introduction to multi-stage trials for developing dynamic treatment regimens
A 45-minute seminar on dynamic treatment regimens (DTRs) and sequential multiple-assignment randomized trials for a clinical audience.
Oct 22, 2021 7:30 AM — 8:30 AM Virtual
Nicholas J. Seewald
Slides
A brief introduction to multi-stage trials for developing dynamic treatment regimens
Sequential, Multiple Assignment, Randomized Trials (SMART)
A dynamic treatment regimen (DTR) is a prespecified set of decision rules that can be used to guide important clinical decisions about …
Nicholas J. Seewald, Olivia Hackworth, Daniel Almirall
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Budgeting SMART: Sample size and repeated measures with a cost constraint in a longitudinal sequential, multiple-assignment randomized trial
A contributed oral presentation at ENAR 2021.
Mar 17, 2021 3:15 PM — 3:19 PM Virtual
Nicholas J. Seewald, Daniel Almirall
Slides
Budgeting SMART: Sample size and repeated measures with a cost constraint in a longitudinal sequential, multiple-assignment randomized trial
Sample size and timepoint tradeoffs for comparing dynamic treatment regimens in a longitudinal SMART
A contributed oral presentation at JSM 2020.
Aug 4, 2020 10:00 AM — 2:00 PM Virtual
Nicholas J. Seewald, Daniel Almirall
Slides Video Video Script
Sample size and timepoint tradeoffs for comparing dynamic treatment regimens in a longitudinal SMART
Sample Size Considerations for Comparing Dynamic Treatment Regimens in a Sequential Multiple-Assignment Randomized Trial with a Continuous Longitudinal Outcome
Clinicians and researchers alike are increasingly interested in how best to personalize interventions. A dynamic treatment regimen is a …
Nicholas J. Seewald, Kelley M. Kidwell, Inbal Nahum-Shani, Tianshuang Wu, James R. McKay, Daniel Almirall
Cite DOI Supplement arXiv PubMed
Sample size considerations for comparing dynamic treatment regimes in a SMART with a longitudinal outcome
An oral presentation given as part of an invited session at CMStatistics 2019 on “recent advances in methods for dynamic treatment regimes”.
Dec 16, 2019 4:35 PM — 5:50 PM London, GB
Nicholas J. Seewald, Daniel Almirall
Slides
Sample size considerations for comparing dynamic treatment regimes in a SMART with a longitudinal outcome
Sample size considerations for comparing dynamic treatment regimens in a sequentially-randomized trial with a continuous longitudinal outcome
A contributed oral presentation at the 2019 Society for Clinical Trials Annual Meeting.
May 20, 2019 2:00 PM — 3:00 PM New Orleans, LA, USA
Nicholas J. Seewald, Kelley M. Kidwell, Inbal Nahum-Shani, Tianshuang Wu, James R. McKay, Daniel Almirall
Slides
Sample size considerations for comparing dynamic treatment regimens in a sequentially-randomized trial with a continuous longitudinal outcome